(through 2020-21)
| Rank | Player | GP | PIM |
|---|---|---|---|
| 1 | Dennis Bonvie | 871 | 4,493 |
| 2 | Rob Murray | 1018 | 2,940 |
| 3 | Peter Vandermeer | 611 | 2,772 |
| 4 | Francis Lessard | 566 | 2,682 |
| 5 | Shawn Thornton | 605 | 2,478 |
| 6 | Fred Glover | 1201 | 2,402 |
| 7 | Brent Thompson | 635 | 2,084 |
| 8 | Serge Roberge | 493 | 1,974 |
| 9 | Greg Smyth | 361 | 1,970 |
| 10 | Rocky Thompson | 566 | 1,919 |
| 11 | Mike Stevens | 617 | 1,916 |
| 12 | Terry Virtue | 888 | 1,856 |
| 13 | Mike Stothers | 670 | 1,840 |
| 14 | Kris Newbury | 826 | 1,839 |
| 15 | Lou Crawford | 658 | 1,827 |
| 16 | Zack Stortini | 603 | 1,825 |
| 17 | Pierre-Luc Letourneau-Leblond | 486 | 1,820 |
| 18 | Jamie Huscroft | 406 | 1,796 |
| 19 | Sylvain Blouin | 388 | 1,791 |
| 20 | Louis Robitaille | 440 | 1,759 |
Most PIM, Career – 4,493
Dennis Bonvie – Cape Breton, Hamilton, Portland, Philadelphia, Wilkes-Barre/Scranton, Providence, Binghamton, Hershey
Most PIM, Season — 551
Brian McGrattan, Binghamton (2004-05)
Most PIM, Game — 64
Steve Parsons, Wilkes-Barre/Scranton (Mar. 17, 2002 vs. Syracuse)